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 MicroGen results are back. Which bacteria are problematic? 
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Joined: Mon Jun 11, 2018 1:43 am
Posts: 27
Post MicroGen results are back. Which bacteria are problematic?
Hi all. Finally pulled the plug and sent off urine and semen to MicroGen DX for analysis. The company has been pleasant to work with, straight forward, and comprehensive, no complaints there. Samples were sent during the end of a flare (and the semen sample kicked that flare UP).

Current symptoms: right testicle is tender, higher and and closer to my body than normal, feels less "protected" - the ball is closer to the skin, etc.. Constant ache and pain right next to the testicle in the groin, radiates into the pelvic crease and thigh. Swollen, irritated meatus, occasionally bad after peeing. The flare kicks up after ejaculation. Not all ejacs cause it, but it is always cased by ejac.

Results:
Urine sample was completely clean - nothing found even in the DNA sequencing. Sweet.
Semen however is different. Not bad enough to point the finger at it being the problem, but still noteworthy:

Rapid results found a low level of bacteria ( < 10^5). Of this, prevotella bivia was 1.16 x 10^3.

The DNA sequencing found a bit more though:
Lactobacillus iners - 21%
Prevotella timonensis - 14%
Corynebacterium tuberculostearicum - 8%
Ureaplasma parvum - 5%
Staphylococcus epidermidis - 5%
Prevotella melaninogenica - 4%
Finegoldia magna - 3%
Veillonella atypica - 2%
Campylobacter ureolyticus - 2%
Dialister propionicifaciens - 2%
Peptoniphilus harei - 2%
Staphylococcus haemolyticus - 2%

No fungus, no resistance genes.

So, not only am I a bit overwhelmed by the number of bacteria in me, I do not know which are worth doing something about and which could be safely ignored as a root cause of my issues. To the best of your knowledge, which of these could be kicking my ass and which are likely not doing anything noticeable?

Thank you in advance.


Fri Nov 16, 2018 3:30 pm
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Joined: Sun May 01, 2016 9:48 am
Posts: 647
Post Re: MicroGen results are back. Which bacteria are problemati
This is generally why I think these microgen tests are stupid. So what are you supposed to do with this information? At most, possibly one of the bacteria in that list might possibly be responsible for your prostatitis...so what are you going to do? Take a broad spectrum abx that might hit one of the gram neg bacteria in the list? Ok,.but that's probably Cipro which your.doc would have prescribed you anyway without all the pointless testing. Good Lord there are more bacteria in that test result than my morning bowel movement. Useless.


Fri Nov 16, 2018 11:18 pm
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Joined: Mon Jun 11, 2018 1:43 am
Posts: 27
Post Re: MicroGen results are back. Which bacteria are problemati
I completely see your point and am a bit overwhelmed about it all myself. On the one hand, finding something means that there might be something that can be done to help me. On the other, I have no clue what to do. They found a small amount, so it's likely none of these things. Plus I have no clue what bacteria should be normally found in the semen and full tubing all the way through the end of the penis.

I am going to try and see an ID specialist and sent this over to my Uro (no clue if he will be able/willing to do anything with this).

Basically, I am wondering if anyone knows if any of these bacteria are specifically linked with out pelvic/groin issues.


Fri Nov 16, 2018 11:57 pm
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Joined: Tue Apr 12, 2016 11:55 am
Posts: 429
Post Re: MicroGen results are back. Which bacteria are problemati
I've read in studies that the following are capable of causing prostatitis and other pelvic / urinary infections:

Staph. epiderm
C. tuberculo
Ureaplasma

S. haemolyticus, C. ureolyticus, and the Lactobacillus species are probably causes of other diseases / conditions. S. epidermis is a common bacteria, and if in the conditions for profileration, could result in infection. You might look at MicrobeWiki for information regarding associative illnesses and do a search for articles of studies that contain the species and prostatitis. If you need help interpreting the abstract and the results that are summarized, pm me and I'll reply quickly. I have a bachelor's in env. science (biology emphasis), and understanding some of the technical jargon and such is a skill I developed. For the record, a study I looked up shows that S. epidermis was isolated as a conditionally pathogenic (meaning a pathogen that can cause such a condition, and depends on certain conditions to cause it) bacteria in prostatitis patients and was part of 70% of associations with CP.


Sat Nov 17, 2018 7:51 pm
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Joined: Mon Jun 11, 2018 1:43 am
Posts: 27
Post Re: MicroGen results are back. Which bacteria are problemati
Any other insights to this? I saw an ID doctor, and he says that most of these are associated with the mouth. On two weeks of Cipro and Flagyl together right now. Feel like crap. I might have had some spit on my hand when I "provided the sample", thus contaminating the results. If anyone does a semen sample, go with a dry run and avoid my issue.

That said, anything else that jumps out that I should be specific to my ID doc about?


Sun Dec 09, 2018 11:02 pm
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Joined: Tue Apr 12, 2016 11:55 am
Posts: 429
Post Re: MicroGen results are back. Which bacteria are problemati
What's an ID doctor?

Lots of bacteria are associated with the mouth, and skin. Numerous of those are also purportedly common in soil, water, and plants. There's a wide range of different strains though, and I don't know how those figure into it. Are they the same strains as in the mouth/skin? do soil bacteria change into a different strain and then get on my skin or in my mouth? or are these mostly or completely separate and distinct?

What should really be far more worrisome is the amount of the bacteria found. When it's at or above a certain level, then the bacteria are probably at a harmful level, similar to too much iron in the blood or too much probiotics. Thus, the need for antibiotics remains since there is either no other way to reduce their effect, or the other ways that are available produce extreme and/or harmful side effects. I've only read that certain nutrients are capable of breaking down the biofilms that bacteria secrete, and resetting things to normal. If you want a link to web page regarding some of those nutrients, pm me and I'll send it. I read it within the past few days, and am looking at which ones are best for me. The fact of the matter is bacteria are colonizers, and their abilities to survive in a vast array of micro-environments surpasses current understanding that seeks to limit their impacts. I think it's part of why the health industry is at such a disadvantage concerning how to diagnose and treat various conditions and diseases. Those notions aside, it is vital to do something. So, if you want more info that you may not come across soon or later, pm me and I'll send you the link. It's not a scam web site selling a product. It's an article that's written in concise detail about prostate problems, and which nutrients / chemicals are harmful and which ones are healthy and essential. It's too much to get into in a reply, so I'm offering to send the link.


Mon Dec 10, 2018 2:14 am
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Joined: Tue Dec 04, 2018 11:30 pm
Posts: 6
Post Re: MicroGen results are back. Which bacteria are problemati
Can you give us an update on your progression? Any revision of your treatment plan? How are you feeling now?


Sun Dec 16, 2018 4:57 pm
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Joined: Mon Jun 11, 2018 1:43 am
Posts: 27
Post Re: MicroGen results are back. Which bacteria are problemati
I am in the same position I was. Infectious disease doctor saw the results, said that most everything looked like oral or skin bacteria, probably contaminated a bit since these tests are so sensitive. Gave me two weeks each of cipro and flagyl. No real improvement. Now trying 10 days of cipro and clindamycin. We shall see.

Seeing a new uro next week, double checking for muscular issue with a pelvic PT, had a TRUS that looked 100 % normal. Asking my PCP for a endocrinologist referral because I haven't had many hormones checked. Running out of ideas


Sun Dec 16, 2018 5:29 pm
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Joined: Tue Apr 12, 2016 11:55 am
Posts: 429
Post Re: MicroGen results are back. Which bacteria are problemati
What if the skin and mouth bacteria found are partly or completely from the lab. Breathing and being present in the lab. How is the bacteria not susceptible to traversing through mediums (air, water, etc) and contaminating the objective results?


Tue Dec 18, 2018 4:06 pm
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Joined: Mon Jun 11, 2018 1:43 am
Posts: 27
Post Re: MicroGen results are back. Which bacteria are problemati
That is definitely possible. I also sent a urine sample at the same time and nothing at all was found.


Tue Dec 18, 2018 4:44 pm
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Joined: Tue Apr 12, 2016 11:55 am
Posts: 429
Post Re: MicroGen results are back. Which bacteria are problemati
Every time I get a urine sample tested, results are normal. I've never had any other test. No EPS, no PSA, no blood, no TRUS, etc. Even a DRE was 'normal', but uro still diagnosed me with CP due to the various and frequent, long-lasting symptoms I had. I read a study abstract in which a higher number of uncircumsized patients had CBP than circumsized patients, same number patients in the two test groups. Almost every report I read about bacterial infection detected has at least one or two species which are common skin colonizers. Or mouth. If I have infection that was from my skin initially, then it means something other than a urine sample is necessary to identify the bacterial species. Perhaps skin samples (a light scrape, at the level of a simple itch) would suffice, and mouth samples.


Thu Dec 20, 2018 7:16 pm
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