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 Biofilm and Prostatitis? 
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Joined: Sun Nov 28, 2010 12:52 pm
Posts: 149
Post Biofilm and Prostatitis?
Biofilms

New article in PLoS Biology
View new articles, published in advance of their scheduled issue.

Published November 13, 2007
Looking for Chinks in the Armor of Bacterial Biofilms
By Don Monroe--- free lance writer
Researchers are exploring various ways to control the stubborn biofilms that bacteria form on medical devices and in many persistent infections.
In the page reached at this URL you will find the article Looking for Chinks in the Armor of Bacterial Biofilms. http://biology.plosjournals.org/perlser ... =1545-7885

He says, “In addition, biofilms are increasingly blamed for recurrent and chronic infections. The case is clear for the Pseudomonas aeruginosa lung infections that haunt cystic fibrosis patients and for recurrent middle ear infections of Haemophilus influenzae. But biofilms are also prime suspects in a long list of other “itises,” including endocarditis, prostatitis, and conjunctivitis.”


Thu Dec 16, 2010 11:50 am
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Joined: Sun Nov 28, 2010 12:52 pm
Posts: 149
Post Re: Biofilm and Prostatitis?
from an abstract of:
Biofilm Producing Bacteria Found in the Prostate.
Mazzoli S, Biofilms in chronic bacterial prostatitis (NIH -ll) and in prostatic calcifications.
FEMS Immunol Med Microbiol. 2010 August:59 (3);337-44

Certain bacterial infections in the prostate may form biofilms and play a role in chronic inflammation speculates this Italian researcher.
*****
Dr Mazzoli said that this study proves , for the first time that, biofilm-producing bacterial strains are present consistently in chronic bacterial prostatitis and that prostatic calcifications are biofilm-related.


Sat Jan 01, 2011 11:43 pm
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Joined: Sun Nov 28, 2010 12:52 pm
Posts: 149
Post Re: Biofilm and Prostatitis?
from an abstract of:
Biofilm Producing Bacteria Found in the Prostate.
Mazzoli S, Biofilms in chronic bacterial prostatitis (NIH -ll) and in prostatic calcifications.
FEMS Immunol Med Microbiol. 2010 August:59 (3);337-44

Certain bacterial infections in the prostate may form biofilms and play a role in chronic inflammation speculates this Italian researcher.
*****
Dr Mazzoli said that this study proves , for the first time that, biofilm-producing bacterial strains are present consistently in chronic bacterial prostatitis and that prostatic calcifications are biofilm-related.


Sat Jan 01, 2011 11:44 pm
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Joined: Sun Nov 28, 2010 12:52 pm
Posts: 149
Post Re: Biofilm and Prostatitis?
SAVE THE DATE!
May 13, 2011
Basic Science Symposium: Stem Cells in Urologic Diseases

The AUA Foundation, in collaboration with the Society for Basic Urologic Research (SBUR) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), will be presenting the first Annual Basic Science Symposium at the 2011 AUA Annual Meeting in Washington, DC.

When: Friday, May 13 2011; from 1:00 – 6:00 p.m.
Where: Walter E. Washington Convention Center, Room 143 A/B/C, Washington D.C.

The Program Committee has developed an outstanding program that will feature leaders in stem and progenitor cell biology in organ development, disease and repair. The goals of this symposium are to inform the participants of the latest scientific developments in the cellular biology of stem cells, their identification and characterization, their roles in organogenesis, repair and disease. Current barriers to the therapeutic use of stem cells, with a focus on urological diseases will be highlighted and discussed. George Christ, PhD will serve as moderator for the program. Speakers and topics are listed below. For the latest information and updates please visit www.UrologyHealth.org.


Basic Science Symposium: Stem Cells in Urologic Diseases
Program Topics and Speakers
TIME TOPIC SPEAKERS
1:00 Opening Remarks David Jarrard, MD (Wisconsin)
1:05 Introductions/Program Agenda/Relevance of Basic Science to Urological Disease/Practice Deborah Hoshizaki, PhD (NIDDK)
1:15 Keynote Address: What are Stem Cells and What Do We Know About Them? Candace Kerr, PhD (Hopkins)
2:00 A Critical Appraisal of Stem Cells within the Kidney Benjamin Humphreys, MD/PhD (Harvard)
2:45 Identification of Bladder Stem/Progenitor Cells Catherine Mendelsohn, PhD (Columbia)
3:15 Break / Networking Opportunity
3:45 Epithelial Stem Cells and Prostate Regeneration
Michael Shen, PhD (Columbia)
4:15 Moving towards Stem Cell Therapeutics - Pitfalls and Barriers TBD
4:45 Panel Discussion: Regeneration of Functional Urological Tissue(s). What is the Scope of the Problem? George Christ, PhD (Wake Forest)
5:45 Program Wrap-Up George Christ, PhD (Wake Forest)
5:55 Closing Remarks Leo Giambarresi, PhD (AUA Foundation)

Supported in part by Wake Forest Institute for Regenerative Medicine


Sun Feb 27, 2011 12:30 am
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Joined: Mon May 09, 2011 4:09 pm
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Location: Tampa, Florida
Post EXPLANATION:::::Re: Biofilm and Prostatitis?
Hello gentlemen,
There is one organism that is believed to be involved in CPPSIII - Chronic Prostatitis that produces biofilm, calcification and inflammation secondary to the biofilm and that is Calcifying NanoParticles (CNP) formerly called Nanobacteria. (They are rarely called Nanobacteria any more for a reason: They do not meet the standard microbiological criteria for "Living". Hence the nomenclature change. But, viruses and prions are not living either, yet cause diseases) These infectious CNPs have been involved in many basic science and clinical studies and have been the subject of many studies published in many/various prominent journals by NASA, Baylor, Univ Illinois, UCSF, Mayo Clinic, Cleveland Clinic and literally scores of other research institutions. CNPs are not able to be detected by routine urology tests, semen evaluations or even standard clinical microbiological methods. They are from 50-500nm (nanometers) in size and electron microscopy is required to see them. They replicate every 3-6 days (rather than in minutes as do "regular" bacteria & viruses.....so routine culturing methods will not discover them. That being said, Just because a standard lab exam & microscopy/culture on your prostatic secretions comes up as negative.......you could still have a problem with a CNP infection....

CNPs have been shown to cause calcification & biofilm in the prostate and other tissues. A study was conducted to evaluate a therapy designed to treat CPPSIII in severe patients that were unresponsive (failed) to all other known therapies for CPPSIII. This study also tested for calcification in the prostate and the presence of CNPs (called Nanobacteria at the time of the study). The study was conducted by a researcher known to most of you: Daniel Shoskes, MD at the Cleveland Clinic. You can read Dr. Shoskes full study as he published in Journal of Urology ..... Click this link to read the study or copy & paste into your browser: http://prostatitis.org/redirect.php?lin ... rology.pdf

Not all of the answers are yet available, but these CNPs appear to be the direct cause of prostatic stones and calcification-related CPPSIII and can clearly be present & problematic even after your urologist says there is no infection by standard clinical evaluations.....also important for you to know: the fluoroquinolone class of antibiotics will not affect CNPs (Nanobacteria) and will not kill them. FYI: the name of the medication combination that was used by Dr. Shoskes in his CPPSIII study was Urobac. Larger clinical studies are planned. Urobac is now a non-prescription compound shown to eradicate Nanobacteria and their pathological calcification. Many cases of BPH & CP will have "prostate sand" or "prostate stones". Our R&D shows the stones are of the very same material that Nanobacteria build upon themselves....Calcium oxalate. Dr Shoskes' study showed eradication of those deposits....prostate sand & prostate stones. Urobac is available online at http://www.NanoBiotechPharma.com and through participating Urologists medical practice.

I am here to help, am not here to promote. I am here as an expert resource for calcification-related, CNP-related CPPSIII & will answer questions for you. I am giving you full disclosure below.

Sincerely,
Gary S. Mezo, CEO (Retired from Family Practice & Emergency Medicine after 28 years, now full-time CEO & Researcher)
Researcher & developer of Urobac. I commissioned Dr. Shoskes Cleveland Clinic Study.
NanoBiotech Pharma
Orlando, Miami & New York City
http://prostatitis.org/redirect.php?lin ... pharma.com
You may send private emails if you like to: gmezo@nanobiotechpharma.com and I will try to answer your questions. Realize please that I no longer have a clinical family practice and you cannot be a "patient" of mine.

_________________
Gary S. Mezo, CEO (Retired ARNP and PA-C)
NanoBiotech Pharma
Tampa, Florida
Prostatitis@nanobiotech.us
www.NanoBiotech.us


Last edited by GMezo on Thu Feb 09, 2017 12:39 pm, edited 1 time in total.



Mon May 09, 2011 5:33 pm
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Post Re: Biofilm and Prostatitis?
great info.


Thu Feb 09, 2017 5:50 am
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Post Re: Biofilm and Prostatitis?
GMezo, are there any other medications that will kill nanobacteria? I need to avoid meds where renal excretion is the primary elimination route.


Thu Feb 09, 2017 11:32 am
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Joined: Mon May 09, 2011 4:09 pm
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Location: Tampa, Florida
Post Re: Biofilm and Prostatitis?
RESPONSE: UROBAC was specifically designed to eradicate Nanobacteria, their lipopolysaccharide biofilm (LPS) and the pathological calcification they deposit and found in the urogenital tract and prostate. Read more at http://prostatitis.org/redirect.php?lin ... Pharma.com
UROBAC does not require a prescription. You can read the Journal of Urology clinical study conducted & published by prostate expert Daniel Shoskes, MD (Cleveland Clinic) on his experience with UROBAC in 19 of his very worst CPPSIII patients that failed on all previous therapies. For publishing purposes, Urobac was called comET as a generic name for the journal of Urology paper. We now know that tetracycline is not required. Best, Gary Mezo,-NanoBiotech Pharma

_________________
Gary S. Mezo, CEO (Retired ARNP and PA-C)
NanoBiotech Pharma
Tampa, Florida
Prostatitis@nanobiotech.us
www.NanoBiotech.us


Thu Feb 09, 2017 12:46 pm
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Post Re: Biofilm and Prostatitis?
Thanks GMezo, do you have data on Urobac's pharmacokinetics? Absorption, distribution into tissues, metabolism, and excretion? Just curious, I'd love to see this data if you have it available. I have to be so careful about what I'm taking due to nephritis. Thanks!


Thu Feb 09, 2017 1:45 pm
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Joined: Tue Feb 23, 2016 6:49 pm
Posts: 133
Post Administrator
Where exactly can I order urobac? Can't seem to find it in my country.

Any side effects of taking it? Considering it doesn't require an prescription.

Why does it say on drugs.com that Ciprofloxacin contains Urobac? Or is it the other way around, urobac contain's cipro components?
Source: http://prostatitis.org/redirect.php?link=
https://www.drugs.com/international/urobac-forte.html

What does this warning letters mean on urobac?
http://prostatitis.org/redirect.php?lin ... 435675.htm


Last edited by Administrator on Fri Feb 10, 2017 8:38 am, edited 1 time in total.

prostate2010



Fri Feb 10, 2017 8:15 am
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Joined: Sun Nov 06, 2016 12:59 am
Posts: 308
Post Re: Biofilm and Prostatitis?
Twister wrote:
Where exactly can I order urobac? Can't seem to find it in my country.

Any side effects of taking it? Considering it doesn't require an prescription.

Why does it say on drugs.com that Ciprofloxacin contains Urobac? Or is it the other way around, urobac contain's cipro components?
Source: http://prostatitis.org/redirect.php?lin ... forte.html

What does this warning letters mean on urobac?
http://prostatitis.org/redirect.php?lin ... 435675.htm



you can order it online. Which country you do live Twister?


Sat Feb 11, 2017 5:33 am
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