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 Guaifenesin (Mucinex) for urologic disorders 
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Joined: Sat Jun 25, 2016 1:51 am
Posts: 100
Post Guaifenesin (Mucinex) for urologic disorders
Found some interesting research in this patent on Guaifenesin and its effects on the prostate:

http://www.google.com/patents/EP0271127A2?cl=en

Quote:
The men were given 400 to 600mg of guaifenesin for 2 to 14 months. Results included a decrease in: (a) semen viscosity; (b) white blood cell count, pH, bacterial content of ejaculated semen, an increase in semen zinc content and semen antibacterial factors as tested against known bacterial strains and (c) sperm mobility. Two unexpected findings were: 1. The reduction, in some patients, of their sperm counts; and 2. A decrease in prostatic size in selected long-term patients as measured by rectal exam, voiding studies, residual bladder urine and bladder and prostatic ultrasound.

If the agent acts by lysing thick prostatic and seminal vesicle secretions, one would expect that theoretically trapped bacteria would "pour" forth and cause increased dysuria and frequency in patients with prostatic and seminal vesicle infections. This in fact does occur in at least one-third of the patients to some degree and most patients should be covered by antibacterial agents initially.


Tue Jun 28, 2016 1:00 pm
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