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 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Sun Apr 16, 2017 9:31 pm 

Replies: 96
Views: 22033

'Tis true, any and all anti-B's can disrupt gut flora, and C-Diff can be fatal. When it comes to Black Box Warnings though, Cipro gets the prize: "Fluoroquinolones, including Cipro, have been associated with disabling and potentially irreversible serious adverse reactions from different body sy...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Sun Apr 16, 2017 2:30 pm 

Replies: 96
Views: 22033

From what I've read, oral fosfo only works for urinary infections through absorption from the urine itself. Apparently it does spread all the way to the testes, as that's where my primary symptoms were. Relapsing epididymitis due to chronic haemophilus infection in the prostate. IV fosfomycin has be...

 Forum: Prostatitis Discussion   Topic: Advice plz or suggestions

Posted: Sun Apr 16, 2017 2:49 am 

Replies: 20
Views: 4517

Hi tolme, & sorry you're having such a tough time. One thing you can do while you wait for urology is to ask your GP about a semen culture (and sensitivity). Both Cipro and trimethoprim penetrate the prostate well, but duration of therapy is typically a month to 6 weeks for effective treatment. ...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Sat Apr 15, 2017 1:38 pm 

Replies: 96
Views: 22033

Hi CHIP, My "condition" started out as a bout with epididymitis on my right side last June, which doxy seemed to knock down quite well. 5 weeks later it was back (again on my right side), so I went back on doxy and was referred to a uro by my GP. By the time I got an appointment with my ur...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Tue Apr 11, 2017 9:52 pm 

Replies: 96
Views: 22033

I started the fosfo several weeks after my third doxy failure, & took it solo... No other drugs combined with the fosfo.

 Forum: Prostatitis Discussion   Topic: Fosfomiycin? Anyone?

 Post subject: Re: Fosfomiycin? Anyone?
Posted: Tue Apr 11, 2017 2:27 am 

Replies: 2
Views: 786

Fosfo was used as a solo therapy in most all the studies I have seen, with up to 85% success, even against resistant organisms where other more dangerous meds had failed. 3 grams daily for a week, continuing with 3 grams every other day (48 hours) for 3 to 5 more weeks. Very few side effects, and al...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Tue Apr 11, 2017 2:15 am 

Replies: 96
Views: 22033

No, after 3 failed try's with doxy, I went on fosfo, and was on no other med combination. Resistance to fosfo has been documented to develop swiftly with E-Coli, which is why it historically has not been used for extended therapy. I haven't read theory as to how fosfo appears to be working with exte...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Mon Apr 10, 2017 2:49 am 

Replies: 96
Views: 22033

OK, I'm still getting quite a few PM's regarding my experience with fosfomycin, so I thought I'd post some links as a reference of what I've learned for new members interested in this therapy. Any member can locate/isolate all my posts by clicking on my handle "Metanoia", and then looking ...

 Forum: Prostatitis Discussion   Topic: Alternate options to Doxy & Cipro?

Posted: Mon Apr 10, 2017 1:15 am 

Replies: 2
Views: 836

I had negative urine cultures and two failed rounds of Doxy myself. After the second failure, I asked for a semen culture and haemophilus turned up. You really need a semen culture (preferably at least 30 days after last antibiotic therapy) to get an accurate culture of prostatic fluid (which makes ...

 Forum: Prostatitis Discussion   Topic: CPPS/IC Clinical Studies & Naturopathic Medicine

Posted: Fri Mar 10, 2017 2:12 am 

Replies: 25
Views: 6016

Watch out for kidney damage from high dose quercetin.

Don't know how much is too much, but give it a googel: quercetin, kidney damage

If you've got high Blood Pressure or Diabetes, kidneys may be susceptible to stress from high dose Q.

 Forum: Prostatitis Discussion   Topic: Has anyone taken macrobid? Safety?

Posted: Fri Mar 03, 2017 2:18 am 

Replies: 2
Views: 940

I have no personal experience with Macrobid, but it's supposed to have less allergic potential than sulfa and far fewer horror stories of persistent & disabling side effects like quinolones/Cipro. I haven't heard Macrobid effectively penetrates into the prostate though. If your infection is in y...

 Forum: Prostatitis Discussion   Topic: My Broth culture shows growth. Which Abx is safe?

Posted: Thu Mar 02, 2017 12:13 am 

Replies: 12
Views: 1581

Your bug may be sensitive to several antibiotics, but to be effective, the antibiotic must penetrate the prostate tissue, if the infection is in the prostate. Anti-B's that penetrate the prostate well are a very short list of quinolones (Cipro), sulfa (TRIM/SULFA), and fosfomycin, which is not on yo...

 Forum: Prostatitis Discussion   Topic: Cystoscopy - yes or no?

 Post subject: Re: Cystoscopy - yes or no?
Posted: Wed Feb 15, 2017 2:08 am 

Replies: 4
Views: 1241

To scope, or not to scope... That is the question! I've never had one, but I'm a surgical technologist and have assisted in may of these procedures... Helped with one today in fact. A cystoscopy looks primarily at the bladder. The doc might visualize the urethra in the area where the prostate surrou...

 Forum: Prostatitis Discussion   Topic: Does Bactrim give any bad nasty side effects?

Posted: Sat Feb 11, 2017 1:19 pm 

Replies: 13
Views: 2788

I posted here: http://forum.prostatitis.org/viewtopic.php?f=2&t=1885 about a problem noted in one paper, the more allergenic component of Bactrim (Sulfamethoxazole) didn't seem to penetrate the prostate well enough to be a significant therapeutic agent: “The prostatic concentration of sulfametho...

 Forum: Prostatitis Discussion   Topic: Does Bactrim give any bad nasty side effects?

Posted: Fri Feb 10, 2017 10:15 pm 

Replies: 13
Views: 2788

Sulfa is notorious for allergic reactions... Mostly dermal/skin rashes, and sometimes these are quite impressive. Google: "sulfa rash" and click on "images" in the search result. Some less frequent side effects here: http://prostatitis.org/redirect.php?link=https://en.wikipedia.o...

 Forum: Prostatitis Discussion   Topic: Dealing with Doctors / Fosfomycin for Prostatitis

Posted: Fri Feb 03, 2017 1:36 am 

Replies: 6
Views: 2136

Thanks Inflamed. I'm about done crowing about my fosfomycin miracle cure, but wanted to help those who want to try it. I realize my haemophilus infection was atypical... I'm just so glad I got to avoid rolling the dice with sulfa/Cipro, I can't help shouting about it from the roof-tops. Godspeed, &a...

 Forum: Prostatitis Discussion   Topic: Administrator

 Post subject: Administrator
Posted: Thu Feb 02, 2017 2:44 am 

Replies: 0
Views: 1322

When my urologist first diagnosed me with acute bacterial prostatitis, he said “now that bacterial resistance to fluoroquinolones has become so widespread, he now recommends Bactrim as his preferred initial treatment”. As I dug into research regarding this therapy, I discovered an interesting paper ...

 Forum: Prostatitis Discussion   Topic: Fosfomycin, where to get?

 Post subject: Administrator
Posted: Thu Feb 02, 2017 1:14 am 

Replies: 9
Views: 2982

Very sorry to hear of this Twister. It may still be possible to get fosfomycin in Sweden if you can find a doctor interested in trying it, as it seems to be available all over Europe. It may require your doc to request import by special permission, but it shouldn't be forbidden. I know in the US, IV...

 Forum: Prostatitis Discussion   Topic: Dealing with Doctors / Fosfomycin for Prostatitis

Posted: Wed Feb 01, 2017 9:41 pm 

Replies: 6
Views: 2136

I had a positive culture for haemophilus that was beta-lactam resistant (beta lactamase positive), but the growth was too small to get a proper sensitivity. There's a different protocol for haemophilus cultures that involves enriched C02 atmosphere for better growth. I took Monurol brand Fosfomycin ...

 Forum: Prostatitis Discussion   Topic: Dealing with Doctors / Fosfomycin for Prostatitis

Posted: Wed Feb 01, 2017 3:27 pm 

Replies: 6
Views: 2136

There are many reports of successful treatment of resistant prostatitis with fosfomycin. Here are a couple of papers from legitimate sources you may wish to print and take with you when you see your doctor for treatment. Fosfomycin An Option for Prostatitis (from renal & urology news) http://pro...

 Forum: Prostatitis Discussion   Topic: Fosfomycin, where to get?

Posted: Wed Feb 01, 2017 3:10 pm 

Replies: 9
Views: 2982

Don't know where your located, but Fosfo should still be available pretty much worldwide. http://prostatitis.org/redirect.php?link=http://www.antimicrobe.org/drugpopup/Fosfomycin%20-%20Brand%20names.htm Fosfomycin Brand names/Manufacturer: AFOS (Salus - ITALY) BIOCIN (Ibirn - ITALY) BIOFOS (Lebens -...

 Forum: Prostatitis Discussion   Topic: Dealing with Doctors / Fosfomycin for Prostatitis

Posted: Wed Feb 01, 2017 5:35 am 

Replies: 6
Views: 2136

Despite recent research and studies regarding fosfomycin’s ability to penetrate the prostate and effectively treat even resistant organisms, little progress has been made on adopting it for routine initial therapy. Doctors tend to prefer their tried and true meds (sulfa & quinolones), despite gr...

 Forum: Prostatitis Discussion   Topic: List of Medications for Bacterial Prostatitis

Posted: Wed Jan 25, 2017 1:03 am 

Replies: 13
Views: 5749

Here's a rather wonky paper on: Penetration of Antimicrobial Agents Into the Prostate http://prostatitis.org/redirect.php?link=http://home.swipnet.se/isop/Penetration.pdf I expect tissue concentrations would need to be matched to the MIC (minimum inhibitory concentrations) for one's particular patho...

 Forum: Prostatitis Discussion   Topic: Ha's anyone used united medical lab for seen culture?

Posted: Tue Jan 24, 2017 3:05 am 

Replies: 1
Views: 731

Your GP should be able to order a semen culture. It's no more difficult than a urine culture.

Ask and ye shall receive!

 Forum: Prostatitis Discussion   Topic: List of Medications for Bacterial Prostatitis

 Post subject: Administrator
Posted: Mon Jan 23, 2017 9:45 pm 

Replies: 13
Views: 5749

Here's the Full Monty on tissue penetration of prostate for Fosfomycin & CBP. http://prostatitis.org/redirect.php?link=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776017/ It appears concentration in prostate tissue has been measured at 4 ug/g (micrograms per gram of tissue), but not clear what...
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