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 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Mon May 08, 2017 11:26 pm 

Replies: 96
Views: 22027

I took 3 grams daily for 5 days, and then dropped down to 48 hour dosing (every other day) for another 3 weeks. From what I've read, fosfomycin is quickly filtered out by the kidneys, and this is why it doesn't work well for things like pneumonia, sore throat or other infections outside the urinary ...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Mon May 08, 2017 7:35 pm 

Replies: 96
Views: 22027

I believe the big guns anti-B's quinolones (Cipro) & sulfa (Bactrim) may produce a more dramatic initial response. Doxycycline even gave me quicker results than I saw with fosfo. The doxy stopped working on my third relapse though. 14 days & I still wasn't any better than on day 1. What coun...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Sun May 07, 2017 8:46 pm 

Replies: 96
Views: 22027

I didn't notice much improvement for the first 2 weeks. Was really worried it wasn't working myself at first.

Prostate massage? Ejaculation was as close to this as I got, but the muscular spasm and cleaning the pipes did seem to help.

Hope you see some improvement soon!

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Sat May 06, 2017 3:12 am 

Replies: 96
Views: 22027

I agree with the sexual activity while on antibiotics , & I practiced this too. The muscular spasm during ejaculation logically should help shake things up, and as long as the antibiotic is present, any spread of bacteria should not occur or would be swiftly killed once outside the prostate. Sem...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Fri May 05, 2017 1:23 pm 

Replies: 96
Views: 22027

Thanks for the update gdad.

We need some more success stories with this med to get a consensus on its effectiveness.

Fingers crossed this treatment holds for you and symptoms continue to resolve!

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Thu May 04, 2017 11:17 pm 

Replies: 96
Views: 22027

Some protocols utilize 48 hour dosing, but most dose daily for the first week. I dosed daily for 5 days without seeing much improvement at all, but began seeing a full recovery on 48 hour dosing around 10 days later. When I first started on fosfo, I wanted to dose daily for as long as possible, but ...

 Forum: Prostatitis Discussion   Topic: Fosfo - Side Effect

 Post subject: Re: Fosfo - Side Effect
Posted: Thu May 04, 2017 8:08 pm 

Replies: 5
Views: 1282

Not that I've heard of. A pharmacist would probably be the best source for info on this. They've got experience with drug interactions, and a database at their fingertips.

Are the palp's persisting?

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Thu May 04, 2017 8:05 pm 

Replies: 96
Views: 22027

I had recurring epididymitis (3 bouts over 5 months) that switched sides from the right (2 times) to the left (third relapse). Doxy knocked this back twice for over a month each time. My uro said the fact that it kept returning after several weeks symptom free and the fact that it switched sides ind...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Thu May 04, 2017 1:16 pm 

Replies: 96
Views: 22027

My symptoms didn't show noticeable improvement till around 10 days or so. I had another bout of epididymitis and my left testicle was still hard as a rock and double normal size. Everything normalized during the second 2 weeks of treatment, & I had a full recovery with no further relapses for ov...

 Forum: Prostatitis Discussion   Topic: How Do They Test For Bacteria?

Posted: Thu May 04, 2017 12:20 am 

Replies: 1
Views: 743

Tests for bacteria can range from a simple dip-stick test for nitrates in urine, to urine culture & sensitivity, to semen culture & sensitivity. I had 2 negative urine cultures and asked for a semen culture which turned up haemophilus bacteria. Once you start on anti-B's, most all cultures w...

 Forum: Prostatitis Discussion   Topic: Fosfo - Side Effect

 Post subject: Re: Fosfo - Side Effect
Posted: Thu May 04, 2017 12:08 am 

Replies: 5
Views: 1282

If your bug is gram negative, these give off endotoxin as they die off, which can cause an immune response.

This typically results in a low grade fever (99.5-101). Don't know if palp's might go along with this.

Do you have a thermometer?

 Forum: Prostatitis Discussion   Topic: Fosfo - Side Effect

 Post subject: Re: Fosfo - Side Effect
Posted: Wed May 03, 2017 7:46 pm 

Replies: 5
Views: 1282

Don't know if palp's are possible with fosfo, but they do use massive doses of fosfo IV on some very sick patients without significant problems. Look Here: http://prostatitis.org/redirect.php?link=http://tinyurl.com/mwxlay9 Intravenous fosfomycin for the treatment of nosocomial infections caused by ...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Tue May 02, 2017 11:29 pm 

Replies: 96
Views: 22027

I've never heard of single dosing for prostatitis. Your doc may be getting this protocol in his formulary when he pulls up the info on this drug as it is typically marketed as a one & done treatment for UTI. I wouldn't take this single dose if I had bacterial prostatitis as this might simply res...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Tue May 02, 2017 1:16 am 

Replies: 96
Views: 22027

Fosfomycin is filtered from the blood to urine during the first few hours after you dose. As long as you take your final urination of the evening within an hour after taking it, you should get the maximum effect. Exact timing isn't critical. You just don't want to take it after dinner and then wash ...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Mon May 01, 2017 10:19 pm 

Replies: 96
Views: 22027

Yes, I always dosed my fosfo around half an hour before bed & emptied my bladder shortly after. I really think this nocturnal dosing helps bathe urinary tissues with higher concentrations for a longer period of time, maximizing absorption into tissues. As fosfo is absorbed via urine rather than ...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Fri Apr 28, 2017 10:06 am 

Replies: 96
Views: 22027

My fingers are crossed for you CHIP. I look forward to hearing good news from you SOON!

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Thu Apr 27, 2017 11:55 pm 

Replies: 96
Views: 22027

I was actually concerned the fosfo wasn't working until around day 14. My testicle was still hard as a rock and about double normal size. I was getting a "soft-serve" ice cream like stool during my therapy, but no fecal urgency or watery stool. I really can't say whether or not to tough ou...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Wed Apr 26, 2017 12:19 pm 

Replies: 96
Views: 22027

I've read studies where they dosed fosfo intravenously at a dozen or more grams a day, so I imagine a true overdose would be difficult to occur at a gram a day orally. Other studies where they tried to dose fosfo orally at up to 3 grams/day resulted in "gastrointestinal intolerance", presu...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Mon Apr 24, 2017 3:00 am 

Replies: 96
Views: 22027

Moderate drinking with fosfo shouldn't be a problem, though you probably want to avoid major binges. I'm a daily drinker myself, and typically put away 4 light beers after dinner. I continued to do this throughout my therapy. It would be ESSENTIAL to take your fosfo AFTER you finish your evening tip...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Sat Apr 22, 2017 1:56 am 

Replies: 96
Views: 22027

Thanks Guys, & yes CHIP fosfomycin does penetrate the prostate. I posted on this here: http://forum.prostatitis.org/viewtopic.php?f=2&t=1868 "It appears concentration in prostate tissue has been measured at 4 ug/g (micrograms per gram of tissue), but not clear what doses were used to ge...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Fri Apr 21, 2017 3:53 am 

Replies: 96
Views: 22027

I should add... If you've got the resources, I would definitely go with the dosing one of the two protocols used in the studies I linked to in my posts. In the Greek study (Fosfomycin An Option for Prostatitis) Dr Karaiskos was daily dosing for 7 days, continuing with an additional 5 weeks of 48 hou...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Fri Apr 21, 2017 12:34 am 

Replies: 96
Views: 22027

Hi CHIP, & sorry the levofloxacin wasn't more effective for you and you wound up getting little more than side effects. My first symptom was caramel colored semen, which seemed to burn my plumbing for several hours after sexual activity. This made me think I might be spreading infection. Once I ...

 Forum: Prostatitis Discussion   Topic: Fosfomycin / Monurol for Prostatitis: The Full Monty

Posted: Wed Apr 19, 2017 4:34 am 

Replies: 96
Views: 22027

Thanks for the input LC. I was thinking if the fosfo failed, I was going to go with stand alone trimethoprim rather than the Bactrim combo SMZ-TMP. Problem was, my haemophilus culture wasn't sufficient to get a proper sensitivity done. Haemophilus requires a special enriched CO2 atmosphere to grow w...

 Forum: Prostatitis Discussion   Topic: Advice/reassurance for a new (young) sufferer?

Posted: Mon Apr 17, 2017 12:24 am 

Replies: 3
Views: 1037

Hi guy, & sorry you're having to join this club at such a young age. I'm surprised your uro decided to go with more doxy too as these doc's love their Cipro & Sulfa meds. Doxy does have an anti-inflammatory effect though, so perhaps he's thinking your infection may have been knocked out with...

 Forum: Prostatitis Discussion   Topic: Advice plz or suggestions

Posted: Sun Apr 16, 2017 10:36 pm 

Replies: 20
Views: 4517

Urine cultures are notorious for false negatives, particularly if they are done after the first round of anti-B's. The anti-B's knock out the infection everywhere but inside the prostate, which is encapsulated and difficult to diagnose and treat. A mans plumbing has "valves" that keep urin...
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